TreatmentsXeomin®
Double-filtered down to nothing but the active molecule — smooth, natural results with no additives for your body to resist, placed by board-certified nurse practitioners.

Curious about
Xeomin?
What is
Xeomin?
Xeomin® is a botulinum toxin type A — the same class as Botox — with one defining trait: it's been stripped of everything except the active molecule itself. No accessory proteins, no additives. Just the ingredient that does the work.
That purity isn't a marketing flourish. The complexing proteins in other neuromodulators are what a small number of long-term patients eventually build antibodies against — the quiet reason results sometimes start fading faster year after year. Xeomin gives the immune system nothing to react to.
In the chair, it behaves like the neuromodulator you know: softening within days, full effect around two weeks, and three to four months of smooth, natural movement.
For patients planning years of maintenance — and anyone whose usual brand has quietly stopped lasting — our nurse practitioners reach for Xeomin.
A double-filtration process removes all complexing proteins — the “naked” neurotoxin, and the purest formulation available.
With no accessory proteins, there's nothing for the immune system to build antibodies against over years of treatment.
FDA-approved for frown lines, with onset and three-to-four-month duration on par with Botox.
Priced per unit alongside our other neuromodulators — your provider quotes an exact total before treating, no surprises.
The results you love, with nothing your body doesn’t need.
Product choice is anatomy choice — and history choice. We carry multiple neuromodulators side by side, and when longevity of response matters most, Xeomin's purity is often the right call.
Your Botox Stopped Lasting
Results fading faster each visit can signal antibody resistance — the exact problem a protein-free formulation solves.
You're in It for the Long Haul
Neuromodulators are a years-long habit. Starting pure keeps every future treatment working like the first.
You Want Ingredient Simplicity
If you read labels on everything else, Xeomin is the one neurotoxin that's only its active ingredient.
You Fear the Frozen Look
Precise dosing by our nurse practitioners keeps expression natural — relaxed, never masked.
Purity isn’t
a buzzword.
It’s why results
keep working.
Both are botulinum toxin type A, and both smooth lines the same way. The difference is what surrounds the active molecule: Botox carries accessory proteins from its manufacturing process, while Xeomin is double-filtered until nothing remains but the active ingredient — which is why it's often called the “naked” neurotoxin.
A small number of long-term neuromodulator users gradually develop antibodies to those accessory proteins, and their results start fading faster or stop appearing at all. Because Xeomin carries none of them, there's nothing for the immune system to react to — which is why it's the product we reach for when someone's usual brand has stopped holding.
Onset is comparable to Botox — softening within a few days, full results around two weeks. Duration is the familiar three to four months, on par with the other neuromodulators we carry.
Absolutely. First-timers won't notice a difference in results between Xeomin and Botox — the mechanism and duration are the same. Starting with the purest formulation simply means one less variable over years of maintenance treatments.
Yes — switching between neuromodulators is common and safe. It's especially worth discussing if your recent results have been fading unusually fast, since that's exactly the pattern Xeomin's protein-free formulation exists to solve. Your provider will review your history and dose accordingly.
Where to next?
Related treatment
Botox®
The gold-standard neuromodulator for forehead lines, the 11s, and crow's feet.
Explore the treatmentThe concern it treats
Wrinkles & Fine Lines
Smooth motion lines and etched-in creases
Start from the concernCommon question
How long does Xeomin last?
Xeomin lasts about 3 to 4 months, like the others. Its distinction is purity: it is a "naked" toxin with no added proteins, which may matter if you…
Read the answer
Nothing extra.
Everything you came for.
Medically reviewed by Barbara Kowalczyk, FNP‑BC and Michael Fressola, ACNP‑BC, board-certified nurse practitioners at Skin Med Spa. This page is for education and is not a substitute for a personalized medical consultation.